Avanafil treats erection dysfunction (ED). It works by increasing blood flow to the penis, which helps to maintain an erection. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Avanafil is in a class of medications called phosphodiesterase (PDE) inhibitors. This increased blood flow can cause an erection. Avanafil does not cure erectile dysfunction or increase sexual desire. Avanafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV). Seeking treatment is crucial for those experiencing consistent signs of impotence. Avanafil, an ED medication, can help improve sexual health by promoting a stiff penis when taken as prescribed by a healthcare provider.